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Abnormal Cortisol Levels: Cushing’s Syndrome

Abnormal Cortisol Levels: Cushing’s Syndrome

 

Cushing’s Syndrome, also known as hypercorticism and hyperadrenocorticism is a hormonal disorder caused by excessive exposure to high levels of cortisol. It may also occur if one takes too much steroid hormones.

This neurotransmitter is affected by Calm PRT and AdreCor

What are the causes of Cushing’s Syndrome?

Cushing syndrome may be caused by taking too much corticosteroid medications like prednisolone and prednisone. These drugs are usually used to treat rheumatoid arthritis and asthma.

 

Cushing’s syndrome can also be caused by too production of cortisol in the body due to excessive concentration of ACTH which stimulates adrenal glands to produce cortisol. Pituitary tumors may cause this condition. Other tumors that can increase the levels of cortisol are adrenal tumors, other cortisol-producing tumor and tumor located anywhere in the body that produces ACTH. Examples of which are tumors of the lungs, pancreas and thyroid.

 

What are the symptoms of Cushing’s Syndrome?

  • §  Upper body obesity
  • §  Thin legs and arms
  • §  Moon facies (red, round, full face)
  • §  Slow growth rate in children
  • §  Purple striae or marks on the skin of the thighs, abdomen and breast
  • §  Thin skin
  • §  Skin bruising
  • §  Acne and other skin imperfections
  • §  Buffalo humps
  • §  Backache which usually occurs during routine activities
  • §  Muscle weakness
  • §  Thinning of the bones which may result to spine and rib fractures
  • §  Excessive hair growth on chest, face, abdomen, neck and thighs
  • §  Irregular or cessation of menses
  • §  Decreased fertility in men
  • §  Decreased libido
  • §  Impotence
  • §  Mental changes such as anxiety, depression or behavioral changes
  • §  Headache
  • §  Fatigue
  • §  Increased blood pressure
  • §  Frequent urination
  • §  Increased thirst

 

How does Cushing’s Syndrome treated?

Mode of treatment greatly depends on the cause. If it is resulted from excessive intake of coriticosteroids, the drugs are slowly decreased. If it is not possible to stop the medication because of an underlying disease, bone thinning or osteoporosis, high cholesterol levels and high blood sugar should be closely monitored.

 

If the Cushing Syndrome is caused by tumors, it is necessary to surgically remove the tumor. If the tumor cannot be removed, patient should be given medications to help block the release of cortisol. 


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