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Cortisol Deficiency Symptoms

Cortisol Deficiency Symptoms


The adrenal glands are responsible for producing various hormones necessary for our survival. These small glands are located above each kidney and each of them is composed of 2 sections namely the cortex and medulla. Cortex is the outer layer of the gland while the medulla is inner part. Both of them are responsible for producing a specific hormone. The cortex is responsible for the hormone cortisol which is stimulated by adrenocorticotropin from the pituitary glands. However, there are cases wherein the adrenal glands secrete cortisol at lower levels than normal. This hormonal disorder is known as hypoadrenalism than can lead to cortisol deficiency. Insufficient cortisol, if not treated early, can be fatal.

This neurotransmitter is affected by Calm PRT and AdreCor

The functions of the adrenal glands are dictated by the pituitary gland. The pituitary gland has the ability to detect the concentration of cortisol in the blood. The gland will release more adrenocorticotopin if the cortisol is low. But if the pituitary gland does not release the hormone despite the low levels of cortisol, or if the adrenal glands do not produce enough cortisol, then you may suffer from cortisol deficiency. 


There are various reasons that can cause cortisol deficiency. One of which is the Addison’s disease, a medical condition wherein the adrenal glands fail to produce cortisol. It is commonly resulted from problems with the immune system. For some reasons, the immune system produces antibodies that attack healthy cells instead of virus and bacteria. In this case, the immune system attacks the adrenal cortex, thus damaging the gland. Other reasons, though rare, are HIV, certain cancers, sarcoidosis and certain drugs.


Secondary hypoadrenalism on the other hand, occurs when the pituitary gland is damaged and loses its ability to produce enough adrenocorticotropin. In this condition, the pituitary gland cannot detect the difference between abnormal and normal levels of cortisol.


Individuals suffering from cortisol deficiency may experience the following symtoms:

  • §  Dizziness
  • §  Weakness and fatigue
  • §  Unintentional weight loss
  • §  Stomachaches
  • §  Skin pigmentation
  • §  Easily depressed
  • §  Difficulty focusing
  • §  Muscle and joint pains


In this case, it is critical to see a doctor for further observation and immediate attention. 

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