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GABA and GABA Supplements

GABA and GABA Supplements

This neurotransmitter is affected by Avipaxin, LoraQuil, Taurine, and Nuvoxil

As people continue to look for natural and safe solutions against anxiety, GABA supplements become quite popular and are getting more and more attention everyday. But, can they really deliver what they promise?


What is GABA?

GABA, known as the gamma-aminobutyric acid medically, is an amino acid made from glutamate in the brain. It functions as one of the primary inhibitory neurotransmitter, blocking nerve impulses to prevent nerve cells from firing frequently and easily. GABA is especially abundant in the cerebral cortex, where sensations and thinking are being interpreted.


Aside from being an inhibitory neurotransmitter, it also elevates the production of alpha waves which is associated with increased mental alertness and relaxed feeling. Moreover, it also lowers beta waves that contribute the state of nervousness, hyperactivity and racing thoughts.


GABA has rhythmic and calming effects on the brain’s electrical impulses. A balanced brain normally receives smooth, regular electrical impulses


GABA Deficiency Symptoms

GABA deficiency is quite common nowadays as stress and environmental factors continue to deplete its levels. Examples of which is coffee which contains caffeine that blocks the release of GABA. Less GABA means increased transmission of the nerves.


Medical conditions associated with insufficient amounts of GABA include the following:

  • Irritability
  • Anxiety symptoms
  • Increased blood pressure
  • Headaches
  • Seizures and epilepsy
  • Palpitations
  • Cardiac problems
  • Low sex drive


GABA and the Blood-Brain Barrier

The blood-brain barrier is the brain’s way of protecting itself against invading chemicals, toxins and potentially hazardous substances. It is a system consists of vascular endothelial cells, epithelial cells, choroid plexus and the arachnoid membrane. The combination of these tissues regulates and restricts the flow of substrates between the central nervous system and the circulatory system.


Research on GABA Supplements

Most drugs manufactured had focused more on the interaction of GABA and certain drugs and its role in different diseases. However, there are little studies to date about how well the GABA actually penetrates the blood brain barrier in order for it to actually receive its calming effect.



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