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Histamine Blockers Plus

Histamine Blockers Plus


Histamine is a chemical substance in the body that reacts against foreign invading bodies. Along with other similar chemicals, it initiates the inflammatory response and produces several symptoms that are commonly known as allergic reaction.


In order to tell the individual cells what to do in response to it, histamine binds with specific receptors on the cell surface. There are 2 receptors that interpret the message of histamine to the cells. They are called H1 and H2 receptors. In order to suppress the effects of histamine on the cells, histamine blockers are prescribed by physicians.

This neurotransmitter is related to AdreCor, ExcitaPlus, and NorLox.


When histamine binds with H1 receptors, the symptoms associated with allergy manifest, such as itchiness, runny nose, watery eyes, clogged sinuses, hives, rashes and many other symptoms. This is usually in response to presence of allergens. Minute particles such as dust and pollen produce an allergic reaction and so do some foods, chemicals and medicines.


The common histamine blockers to keep the histamine from binding with H1 receptors are appropriately called antihistamine. These medicines are very effective. Common examples of antihistamines are dimenhydrinate, diphenhydramine, loratadine, cetirizine and chlorpheniramine. The old antihistamines usually have a sedative side effect, which others use to aid in sleeping.


The H2 receptors are responsible for the stimulation of the parietal cells of the stomach to produce more gastric acid. This reaction may cause the irritation of the stomach lining and eventually lead to ulcerations. The histamine blockers used for this are called H2 receptor antagonists. These medications, which include cimetidine, ranitidine and famotidine among others, are used as antiulcerants. However, the newer proton pump inhibitors have now surpassed the H2 blockers in terms of effectiveness and use.


While histamine is an important component of the body chemistry, cases of hypersensitivity need to be neutralized with the use of histamine blockers since some symptoms may cause danger to the individual.

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