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Phenylalanine is converted to the catecholamines in a multi-step enzymatic process. Phenylalanine can also be converted to phenylethylamine (PEA) by amino acid decarboxylase. The D-isoform of phenylalanine may enhance endorphin activity by inhibiting enkephalinase, the enzyme responsible for endorphin degradation. L-phenylalanine stimulates the production of the appetite-suppressing peptide, cholecystokinin (CCK).
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