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Norepinephrine and Hyperarousal

Norepinephrine and Hyperarousal

Norepinephrine functions both a neurotransmitter and hormone in the body. It is classified as a catecholamine hormone which is significant in the body's fight or flight response. This hormone, also known as noradrenaline works hand in hand with epinephrine or adrenaline in responding to threatening and stressful situations. However, norepinephrine is related more to maintaining a normal heart rate, blood pressure and sugar levels as compared to adrenaline which gives the muscles the much needed boost to respond to certain situations. As neurotransmitters, they are classified monoamines. As a neurotransmitter, it is important for attentiveness, emotions, sleeping, dreaming, and learning. Norepinephrine has been suspected to have its role in causing depression since discovering that medications that reduce noradrenaline in the brain leads to depression. Norepinephrine is secreted by the adrenal medulla and is also produced by the nerve endings. 

This neurotransmitter is related to Tyrosine Spray, Daxitrol, AdreCor, Balance D, ExcitaPlus, Calm PRT, and Avipaxin.


A slight rise in norepinephrine levels in the body produces heightened arousal which is considered a pleasurable experience. Several street drugs that make one high such as cocaine and amphetamines increase the brain's level of norepinephrine bringing one to a state of euphoria. Caution must be taken for this pleasurable experience may be addicting.


A moderate increase in levels of norepinephrine may create worry, fears, restless sleep, jumpiness and other reactions that may be attributed to neurotransmitter's involvement in creating physical reactions in the body.


High levels of this chemical substance may cause a continuous feeling of prolonged irritability and anxiety. Muscle tension, jumpiness and a higher rate in heartbeat may also be attributed to high levels of noradrenaline. These are not good symptoms for prolonged high levels of noradrenaline may lead no psychological anxiety disorders. Unusually high levels of noradrenaline may lead to sweating, hyperventilating, tremor and a very fast heartbeat or in a nutshell, a full-blown panic attack.


It should be noted that almost all anxiety disorders involve a rise in the level of norepinephrine in the body, so maintaining the hormones at a normal level is vital to keep a stable psychological state.



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