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Tryptophan Supplements Benefits Dosage and Side Effects

Tryptophan Supplements Benefits Dosage and Side Effects

This ingredient is contained in NeuroScience's Nuvoxil, a popular health product by Neuroscience Inc..


Tryptophan is an essential amino acid that is found naturally in certain protein foods like turkey, cheese, milk and tuna. This amino acid is converted by the body into 5-HTP (5-hydroxy-tryptophan) which then again is converted into serotonin. Serotonin is very important in the regulation of appetite, mood, impulse control and sleep.


Metabolism of Tryptophan

The formula below shows how tryptophan is converted to 5-HTP and serotonin and melatonin.


Tryptophan → 5-HTP → Serotonin → N-acetyl-serotonin → Melatonin


You should take note that Vitamin B6 is a very important element in the metabolism process. Also, you need to know that not all tryptophan are converted into 5-HTP. It may undergo and metabolized using other biological pathways.


Recommended Dosage for Tryptophan Supplements

General recommendation is 500mg to 1000mg. It is also advisable to take the said supplements at night since it can help individuals with sleeping problems.


Benefits of Tryptophan Supplements

People who used these kinds of health supplements have reported that it is useful in alleviating the symptoms of anxiety, thus reducing its occurrences and intensities. However, how tryptophan supplements help alleviate panic attacks are still not clear.


Side Effects of Tryptophan

The most common side effect caused by taking tryptophan supplements is drowsiness. Therefore, it is a good idea that you take it during nighttime and never if you need to drive or operate heavy machineries. However, drowsiness can be beneficial for individuals that are having trouble initiating sleep. Other side effects include dry mouth, dizziness, nausea and loss of appetite. Disorientation and confusion are very rare side effects of tryptophan.


Drug Interaction

Taking tryptophan supplements alongside SSRIs like Paxil, Prozac and Zoloft would not cause you any untoward effects if taken in low dosages. However, cases may vary from patient to patient so it is important that you are supervised by your doctor.

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