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Vitamin D 4000 IU Information

Manufacturer: BioGenesis Click here to Buy Vitamin D 4000 by BioGenesis


- Immunomodulatory - Supports healthy immune function - Supports healthy skin - Cytokine modulator - Supports healthy cartilage and joints - Supports healthy vascular tone - May support healthy blood lipid levels

VITAMIN D is mostly attained through the skin’s exposure to sunlight. Cholecalciferol, also known as vitamin D3, is formed from 7-dehydrocholesterol in the skin after exposure to UV light. Unfortunately, due to the risk of skin cancer, many individuals are limiting sunlight exposure or using liberal amounts of sun protective factors (SPF) in sun screen lotions, both of which limit vitamin D production in the skin. In the body, cholecalciferol is hydroxylated to calcidiol in the liver and then to calcitriol, the active form of vitamin D, in the kidneys. The active form of vitamin D works with parathyroid hormone and calcitonin to regulate serum calcium and phosphorus concentrations.

Vitamin D deficiency causes increased parathyroid hormone activity which acts to maintain serum calcium and phosphate concentrations at the expense of skeletal calcium.

Vitamin D contributes to bone health. Various studies have found an association between low serum levels of vitamin D and joint disorders as well as decreased bone density. In addition, risk for progression of these disorders increases substantially with both low vitamin D intake and decreased serum levels. Some of the best results obtained in studies on bone health have supplemented patients with 700 - 800 IU vitamin D per day, considerably higher than the recommended 400 IU per day. The best results were obtained when vitamin D was given with calcium.

Vitamin D also provides immune and anti-inflammatory support. One researcher described vitamin D as a flexible bidirectional immunomodulator. The cytokines interleukin 1 (IL-1) and interleukin 2 (IL-2) appear to be favorably regulated under the influence of vitamin D.

Benefits of vitamin D extend to skin health. Topical vitamin D analogues have been shown effective in treatment of certain skin disorders. Vitamin D has anti-proliferative activity on keratinocytes and stimulates epidermal cell differentiation.

Additionally, epidemiological data indicates that a low vitamin D status is associated with vascular disorders. Clinical studies have demonstrated an inverse relationship between circulating vitamin D levels and plasma rennin activity. It should also be noted that vitamin D has been shown to inhibit lipid peroxidation.

Click here to Buy Vitamin D 4000 by BioGenesis

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