PectaSol-C® Modified Citrus Pectin (MCP) is a natural product that is derived from the peel pith of citrus fruit. It is formulated to:

• Support healthy cellular growth*

• Promote normal tissue health*

• Gluten and allergen free

• Suitable for vegetarians

PectaSol-C® MCP is a special class of pectin that was developed by Isaac Eliaz, M.D., M.S., L.Ac.. Dr. Eliaz has researched and published articles on modified citrus pectin for over a decade. MCP is protected by US patents #6,274,566, #6,462,029, and #7,026,302. PectaSol-C® MCP is produced using a proprietary process that carefully controls both the molecular weight (MW) and degree of esterifcation (DE). The specific low molecular weight size range of PectaSol-C® MCP allows easy absorption into the bloodstream with the effective range of molecular size and esterification.*

Pectin Chemistry

Pectin is a soluble dietary fiber composed of galacturonic acid and varying amounts of galactose, glucose, rhammose, and arabinose. In its natural state, the galacturonic groups are found esterified. Regular pectin is not absorbed due to its large size, but it nevertheless plays a key dietary role in supporting digestive and cardiovascular health.*

Pectin as an Alternative Ligand for Galectin-3

Aberrant cells that have lost control of their cell cycle tend to proliferate, spread to other parts of the body (metastasis), and stimulate new blood vessel growth (angiogenesis). Researchers have proposed that the invasive tendencies of such cells are supported by the over expression of galectin-3 molecules on their surface. Aberrant cells of the prostate, breast, colon, lung, lymphatic system, skin, brain, larynx & others have been found to express increased numbers of galectin-3 molecules.*

Galectin-3 molecules function by binding to galactose residues on neighboring cells and blood vessels allowing aberrant cells to aggregate and spread. De-esterified pectin is a natural ligand (binder) for galectin-3 (receptor) molecules. When galectin-3 binds to the galacturonic acid in pectin, it is unable to adhere to other cells.*

Early Research on MCP

In the 1990's, researchers demonstrated that oral administration of citrus pectin modified to be less than 10kD and with a low DE would interfere with the ability of aberrant cells to proliferate, adhere to each other, or adhere to the inner walls of blood vessels. Their research suggested that MCP, as a natural ligand for galectin-3, could be a valuable nutritional supplement for supporting cellular health.* 

Pre-Production Research on PectaSol-C® MCP

Dr. Eliaz developed the PectalSol® brand as the first modified citrus pectin for human use. This MCP is designed to be absorbable into the body and a superior ligand for galectin-3 and involved extensive pre-production research. After optimization, PectaSol® was immediately tested clinically. Note that MCP is not a defined term in the dietary supplement industry and as such PectaSol® is the only brand of modified citrus pectin that has been validated in human clinical trials.*

Recent Developments

The modification process was improved in 2008 to produce more pectin molecules in the effective lower range of molecular weight. The drying process has also been improved to produce a finer particle size as well, with more than 90% below 100 microns. This means a better absorbed product. The new recent developments have been clinically demonstrated to benefit the quality of.*

This product is called PectaSol-C® to differentiate the improved modification.

Manufacturing and Quality Control

PectaSol-C® MCP is produced under conditions that meet or exceed good manufacturing practices (GMP) as defined by the FDA.

Contraindications and Cautions: Research has shown no adverse effects or toxicity even with long term use. Since MCP is a dietary fiber, some individuals may experience loose stools at the start of use. Although there are no known drug interactions with MCP, it is recommended that it be taken 2 hours before or after medications or other supplements because dietary fibers have the potential of binding to drugs and may affect absorption.

In the production of PectaSol-C® MCP, the ratio of sodium to potassium is carefully controlled to resemble the ratio naturally present. People with a health condition requiring the restriction of potassium should consult their health care provider before using this product.

How Supplied: Capsules: 90 or 270 capsules per bottle. / Powder: 150 or 454 grams per bottle.

Suggested Use: Capsules: For active support; 6 capsules, 3 times a day. For long term maintenance, 6 capsules daily. Powder: For active support; 1 scoop (5 grams), 3 times a day added to water or juice. For long term maintenance, 1 scoop (5 grams) daily, or as directed by your health care provider. PectaSol-C® is best taken on an empty stomach. An empty stomach is considered 30 minutes before food and 2 hours after meals. 

It is 100% soluble, but due to small particle size, it is best to let it sit a few minutes in the liquid to slowly hydrate the particles before stirring with a spoon. Stirring immediately after adding liquid can cause “stubborn” clumping.

Other ingredients: Vegetable capsule (natural vegetable cellulose, water), stearic acid, magnesium stearate, microcrystalline cellulose, silicon dioxide.

† Percent Daily Values (%DV) are based on a 2,000 calorie diet.

* Daily Value not established.

Additional Usage Guidelines: This product is designed to be taken on an empty stomach, at least 30 minutes before or 2 hours after food, or 2 hours either before or after other supplements or medications.

PectaSol-C® Powder can be mixed with any cool, or room temperature liquid.

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